Precision Medicine

Precision medicine, the tailoring of healthcare based on an individual’s genetics, lifestyle and environment, has been used with success in monogenic diabetes but several barriers have prevented its large-scale application throughout diabetes. Diabetologia published a series of reviews outlining previous achievements, current limitations and future promises of precision diabetes in the May 2017 issue of the journal. We have grouped these articles, along with others published subsequently on the same topic, below.

Precision diabetes: a realistic outlook on a promising approach
Sally M. Marshall
Precision diabetes: learning from monogenic diabetes
Andrew T. Hattersley, Kashyap A. Patel
Genetics of obesity: can an old dog teach us new tricks?
Giles S. H. Yeo
Lifestyle and precision diabetes medicine: will genomics help optimise the prediction, prevention and treatment of type 2 diabetes through lifestyle therapy?
Paul W Franks, Alaitz Poveda
Painting a new picture of personalised medicine for diabetes
Mark I. McCarthy
Pharmacogenetics in type 2 diabetes: precision medicine or discovery tool?
Jose C. Florez
Human genetics as a model for target validation: finding new therapies for diabetes
Soren K. Thomsen, Anna L. Gloyn
New approaches beyond genetics: towards precision medicine in diabetes
Leif Groop
Proteomics for prediction of disease progression and response to therapy in diabetic kidney disease
Michelle J. Pena, Harald Mischak, Hiddo J. L. Heerspink
Diabetes at the crossroads: relevance of disease classification to pathophysiology and treatment
R. David Leslie, Jerry Palmer, Nanette C. Schloot, Ake Lernmark