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When Diabetes Meets the Liver: MASLD in Focus

The cover shows a spotlight on individuals across different stages of life, genders and ethnicities, all linked by metabolic dysfunction-associated steatotic liver disease (MASLD) and diabetes. MASLD is represented by lipid droplets (yellow circles) within the liver, while diabetes is depicted through the pancreas and key insulin target tissues (the liver, skeletal muscle and adipose tissue). The geometric, interconnected design reflects the complexity of inter-organ crosstalk and its dysregulation in these metabolic conditions.

This year’s special issue focuses on the liver and diabetes.

On the cover image, the spotlight is shone on individuals across different stages of life, genders and ethnicities, all linked by metabolic dysfunction-associated steatotic liver disease (MASLD) and diabetes. MASLD is represented by lipid droplets (yellow circles) within the liver, while diabetes is depicted through the pancreas and key insulin target tissues (the liver, skeletal muscle and adipose tissue). The geometric, interconnected design reflects the complexity of inter-organ crosstalk and its dysregulation in these metabolic conditions.

Cover credit: Nayere Taebnia (Karolinska Institutet, Stockholm, Sweden)

A photo of Jennifer plus

Understanding MASLD and diabetes through lived experience - published online 29/07/2026

Jennifer Berg, Paul Cherry, Kent Cheung, Susan Horava, Kim Martinez, Kerry Sivia, Shi Yin & Isobel Walters
Yki‑Järvinen & Michael Roden Key Messages text box

The liver in diabetes: current state and future perspectives - published online 15/08/2026

Hannele Yki-Järvinen & Michael Roden
Wild graphical abstract

MASLD prevalence, incidence and global aspects - published online 21/05/2026

Sarah H. Wild, Jeffrey V. Lazarus, C. Wendy Spearman, Ponsiano Ocama, Josh Bilson, Xiao-Dong Zhou, Ming-Hua Zheng & Christopher D. Byrne
Qadri graphical abstract

Screening and diagnosis of liver disease in diabetes: a guide and evidence‑based assessment - published online 06/08/2026

Sami F. Qadri
Jonuscheit graphical abstract

Imaging of MASLD: clinical standards and novel methods - published online 16/07/2026

Marc Jonuscheit & Vera B. Schrauwen-Hinderling
Gastadelli graphical abstract

Metabolic drivers of MASLD and MASH: from hormonal imbalance to fibrosis - published online 20/06/2026

Amalia Gastaldelli, Egeria Scoditti & Maria Paula Macedo
Bilson graphical abstract

Genetics of MASLD: a diabetes perspective - published online 08/06/2026

Josh Bilson & Hanieh Yaghootkar
Segev graphical abstract

Updates on paediatric MASLD: insights from an endocrine lens - published 13/04/2026

Natalie Segev & Marialena Mouzaki
Stener-Victorin graphical abstract

MASLD, diabetes and PMOS across the female life stages - published online 05/06/2026

Elisabet Stener-Victorin, Sofia Carlsson, Hannes Hagström & Nayere Taebnia
Stefan graphical abstract

Pharmacological treatment of MASH - published online 17/07/2026

Norbert Stefan & Giovanni Targher
Dufour graphical abstract

Non‑pharmacological treatment of MASLD - published online 25/07/2026

Jean-François Dufour & Annalisa Berzigotti
Kahl graphical abstract

Is MASLD an independent risk factor for micro‑ and macrovascular complications of diabetes? A critical reappraisal and future directions - published online 01/08/2026

Sabine Kahl, Cyrielle Caussy & Kenneth Cusi
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