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A systematic review of trends in all-cause mortality among people with diabetes – published online 06/07/2020

Lei Chen, Rakibul M. Islam, Joanna Wang, Thomas R. Hird, Meda E. Pavkov, Edward W. Gregg, Agus Salim, Maryam Tabesh, Digsu N. Koye, Jessica L. Harding, Julian W. Sacre, Elizabeth L.M. Barr, Dianna J. Magliano, Jonathan E. Shaw

Some studies have reported falling mortality among populations with diabetes, but consistency of this trend among various populations with diabetes is unclear. In this issue, Chen and colleagues (https://doi.org/10.1007/s00125-020-05199-0) report a systematic review of 35 studies on the trends in all-cause mortality in people with diabetes from 1970 to 2016. They found that all-cause mortality has declined in nearly 80% of predominantly Europid populations with diabetes from 2000 to 2016. Furthermore, for nearly 60% of the populations, the reduction in mortality seen among those with diabetes was greater than or similar to the reductions observed in those without diabetes. However, there was under-representation of younger age groups and non-Europid populations in the published literature, and lack of mortality data from low- and middle-income countries. Thus, patterns of diabetes mortality remain uncertain in these populations. These findings highlight the significance of maintaining and improving cardiometabolic management in diabetes in order to achieve ongoing reductions in mortality in people with diabetes.

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