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The changing face of paediatric diabetes – published online 02/01/2020

Shah figure

Amy S. Shah, Kristen J. Nadeau

Paediatric diabetes is on the rise. In the last decade there has been extensive research dedicated to understanding its pathophysiology and its associated comorbidities and complications. In this issue, Shah and Nadeau (https://doi.org/10.1007/s00125-019-05075-6) summarise the current state of knowledge of type 1 and type 2 diabetes in children and adolescents. They review the current epidemiology and address the importance of differentiating between the two main types of diabetes, especially in the setting of obesity. The authors go on to  discuss the observed comorbidities and complications in type 1 and type 2 diabetes in youth, pointing out that abnormalities in heart physiology, blood dynamics and renal hyperfiltration are more common in individuals with either type of diabetes than in peers without diabetes. Finally, currently available treatments and novel treatments on the horizon are discussed.  The figure from this review is available as a downloadable slide.

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