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Precision Medicine


Precision medicine, the tailoring of healthcare based on an individual’s genetics, lifestyle and environment, has been used with success in monogenic diabetes but several barriers have prevented its large-scale application throughout diabetes. Diabetologia published a series of reviews outlining previous achievements, current limitations and future promises of precision diabetes in the May 2017 issue of the journal. We have grouped these articles, along with others published subsequently on the same topic, below.

Chung figure

Precision medicine in diabetes: a Consensus Report from the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD) - published online 19/06/2020

Wendy K. Chung, Karel Erion, Jose C. Florez, Andrew T. Hattersley, Marie-France Hivert, Christine G. Lee, Mark I. McCarthy, John J. Nolan, Jill M. Norris, Ewan R. Pearson, Louis Philipson, Allison T. McElvaine, William T. Cefalu, Stephen S. Rich & Paul W. Franks

Diabetes in the older patient: heterogeneity requires individualisation of therapeutic strategies - published online 07/02/2018

Guntram Schernthaner, Marie Helene Schernthaner-Reiter

Human genetics as a model for target validation: finding new therapies for diabetes - published online 26/04/2017

Soren K. Thomsen, Anna L. Gloyn

Precision diabetes: learning from monogenic diabetes - published online 17/03/2017

Andrew T. Hattersley, Kashyap A. Patel

Precision diabetes: a realistic outlook on a promising approach - published online 16/03/2017

Sally M. Marshall

Pharmacogenetics in type 2 diabetes: precision medicine or discovery tool? - published online 10/03/2017

Jose C. Florez

Painting a new picture of personalised medicine for diabetes - published online 07/02/2017

Mark I. McCarthy

Lifestyle and precision diabetes medicine: will genomics help optimise the prediction, prevention and treatment of type 2 diabetes through lifestyle therapy? - published online 25/01/2017

Paul W Franks, Alaitz Poveda

Genetics of obesity: can an old dog teach us new tricks? - published online 24/12/2016

Giles S. H. Yeo
New approaches beyond genetics: towards precision medicine in diabetes - published online 08/10/2016

New approaches beyond genetics: towards precision medicine in diabetes - published online 08/10/2016

Leif Groop

Proteomics for prediction of disease progression and response to therapy in diabetic kidney disease - published online 25/06/2016

Michelle J. Pena, Harald Mischak, Hiddo J. L. Heerspink

Diabetes at the crossroads: relevance of disease classification to pathophysiology and treatment - published online 24/10/2015

R. David Leslie, Jerry Palmer, Nanette C. Schloot, Ake Lernmark